Florida Researchers Develop Medically Safer Hybrid Grapefruit

by | Mar 12, 2013 | Health & Healing

Grapefruit fans who gave up the fruit to avoid potentially dangerous interactions with their prescription medications may soon be able to indulge in the tangy fruit without risk.

Tests on a new hybrid grapefruit developed in Florida found very low levels of the organic chemical compounds implicated in what is known as the “grapefruit juice effect,” said Fred Gmitter, a University of Florida citrus researcher and breeder.

More than 85 drugs may interact with standard grapefruit, 43 with serious side effects, and the number is growing, according to a recent report in the Canadian Medical Association Journal.

Among the drugs which may interact with grapefruit are certain cholesterol-lowering statins, some cancer and heart drugs and antibiotics.

The problem with grapefruit, according to Gmitter, is a family of organic chemical furanocoumarins believed to inhibit enzymes from breaking down certain medication, leading to drugs entering the blood stream in higher concentrations than intended, causing an overdose.

Potential adverse effects include sudden death and kidney or respiratory failure, according to the medical journal.

Gmitter said chemical analysis of the hybrid grapefruit, known for now as UF914, found levels of furanocoumarins at a small fraction of the level in standard grapefruit.

Subsequent tests of the juice in human cell cultures indicated the fruit would not produce harmful side effects, he said. Human clinical trials would be needed to stake an absolute claim that the hybrid has solved the problem of fruit and drug interactions, he added.

As word began to spread about the hybrid to people on medications who had been warned away from grapefruit, Gmitter said, “I’ve gotten phone calls from all around the country … saying, oh my gosh, I miss my Florida grapefruit, when can I have this grapefruit, I miss grapefruit so much.”

The University of Florida is in the process of commercializing the hybrid, a cross between pomelos and red grapefruit, with large-scale production likely five to seven years from now. Discovery of the lower levels of furanocoumarins was a serendipitous bonus in a breeding project Gmitter said was intended to create a sweeter and less bitter variety.

In focus groups the hybrid, which is seedless, and larger, juicier, sweeter and less bitter than a standard grapefruit, won approval from people who liked and didn’t like grapefruit, he said.

CHARISMA NEWSLETTERS

Stay up-to-date with current issues, Christian teachings, entertainment news, videos & more.

The latest breaking Christian news you need to know about as soon as it happens.

Prophetic messages from respected leaders & news of how God is moving throughout the world. 


MORE FROM CHARISMA

Are Domestic Missions as Important as International Missions?

Are Domestic Missions as Important as International Missions?

Huntington, Indiana, is a small town that is witnessing a revival stirring within the youth. For 10 days, I was able to witness this firsthand by the opportunity to lead a trip to this town to serve with six other college girls. During this time, I saw how the Lord...

8 Ways You Can Attract God’s Full Attention

8 Ways You Can Attract God’s Full Attention

We all want God’s attention, right? The best way to get His attention is to give Him our full attention, and pay close attention to what attracts Him. There are certain attitudes and actions which attract God and others that repel Him. We want to create an atmosphere...

What the Holy Spirit Showed Me About the Fentanyl Overdose Crisis

What the Holy Spirit Showed Me About the Fentanyl Overdose Crisis

Fentanyl has been making headlines lately in the midst of an overdose crisis raging in America. Doubtless, if we don’t shut this down in the spirit, this overdose crisis will soon find its way into many other nations. Fentanyl is a powerful synthetic opioid similar to...

Could Judas Have Been Saved?

Could Judas Have Been Saved?

The answer is yes. If Judas would have simply repented to God, he could have been saved. The Bible tells us that everyone can be saved. Judas knew he had sinned but he didn’t bring it to God. A person can feel remorse within themselves, but not remorse for sinning...

Anne Graham Lotz: One Kingdom Truth That Will Never Change

Anne Graham Lotz: One Kingdom Truth That Will Never Change

Out of respect for those of you who have taken the time to comment about a statement I made 11 years ago regarding the World Economic Forum, I thought it would be beneficial to restate God’s call on my life. In 1988, He made it clear that I was to be His messenger,...

RECENT ARTICLES

Spirit-Filled Pastor: Only Pulpits Have the Power to Change America

One thing is crystal clear in America: If we truly want change, we must re-spark biblical boldness and flame the fires of biblical action. If we won't fight, then spiritually speaking, we will fade...
A Big Excuse That Shuts Down Our Ability to Hear from God

A Big Excuse That Shuts Down Our Ability to Hear from God

One of the biggest excuses we have is that we somehow feel God doesn’t speak to us. This excuse shuts down our ability to hear from Him, trust Him and surrender to Him. All three things are integral when we are trying to change our habits, lose weight, get healthy and...

How Do You Leave a Church That Becomes Toxic?

How Do You Leave a Church That Becomes Toxic?

Two weeks ago, I shared several practical guidelines on how to leave a church gracefully. I wrote this because I hear so many stories about people storming out of churches because their feelings got hurt. But one astute reader didn’t appreciate my observations because...

Prophetic Word: There Will Be a Day of Reckoning

Prophetic Word: There Will Be a Day of Reckoning

“Behold, the day of the LORD comes, cruel, with both wrath and fierce anger, to lay the land desolate; and He will destroy its sinners from it. For the stars of heaven and their constellations will not give their light; the sun will be darkened in its going forth, and...

8 Reasons for You to Speak in Tongues

8 Reasons for You to Speak in Tongues

If a person were to ask, “Why speak in tongues?” couldn’t we also ask, “Why pray?” The Word of God shows a definite value in praying with an unknown tongue. Jesus tells us that “it is necessary always to pray” (Luke 18:1, MEV). Later, in speaking of prayer, Paul...

Pin It on Pinterest

[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]
[class^="wpforms-"]