Breast Cancer Patients May Be Able to Skip Chemo, Study Finds

by | Jun 4, 2018 | Health & Healing

Some 70 percent of women with early-stage breast cancer and an intermediate risk of cancer recurrence can safely skip chemotherapy after their tumors have been removed, U.S. researchers said on Sunday.

“This is a major finding,” said Dr. Larry Norton, a breast cancer expert at Memorial Sloan Kettering Cancer Center in New York, who helped organize the government-funded study more than a decade ago.

“It means that maybe 100,000 women in the United States alone do not require chemotherapy,” Norton said.

The research, presented at the American Society of Clinical Oncology (ASCO) meeting in Chicago, studied how to treat women with early-stage breast cancer that responds to hormone therapy.

Women were deemed to have a medium level risk of the cancer coming back based on a 21-gene panel known as Oncotype DX from Genomic Health. The test predicts the likelihood of cancer recurrence within 10 years.

Those who score low on the test – from zero to 10 – are already told to skip chemotherapy after their tumors are removed and they receive hormone therapy. Those who score high – 26 to 100 – receive both hormone therapy and chemotherapy.

The study, dubbed TAILORx, was also published in the New England Journal of Medicine. It involved more than 10,000 women with breast cancer that had not spread to nearby lymph nodes and whose tumors respond to hormone therapy and test negative for the HER2 gene.

Of those, 6,711 scored in the intermediate range of 11-25, and were randomly assigned hormone therapy alone or hormone therapy plus chemotherapy.

The study found that all women over 50 with this type of breast cancer could skip chemotherapy, a group that represented 85 percent of the study’s population. In addition, women 50 and younger who scored between zero and 15 could be spared chemotherapy and its toxic side effects.

However, chemotherapy did offer some benefit to women aged 50 and younger who had a cancer recurrence score of 16-25, researchers found.

Dr. Steven Shak, chief scientific officer at Genomic Health, said about four in 10 women in the United States with early stage breast cancers are not tested for recurrence risk. He expects the study’s results will change that practice.

“This is going to provide the highest level of evidence now for our test being indispensable in clinical practice,” Shak said.

The company currently provides tests to more than 900,000 patients in more than 90 countries, Shak said. In the United States, the test costs $4,000 and is covered by Medicare and all major private insurers. {eoa}

© 2018 Thomson Reuters. All rights reserved.

CHARISMA NEWSLETTERS

Stay up-to-date with current issues, Christian teachings, entertainment news, videos & more.

The latest breaking Christian news you need to know about as soon as it happens.

Prophetic messages from respected leaders & news of how God is moving throughout the world. 


MORE FROM CHARISMA

Charisma Highlights: Is Serial Killer Jeffrey Dahmer in Heaven?

Charisma Highlights: Is Serial Killer Jeffrey Dahmer in Heaven?

Following are snippets of the top stories posted on charismamag.com over the past week. We encourage you to visit the links to read the stories in full. Is Serial Killer Jeffrey Dahmer in Heaven? Is it possible that behind the pearly gates of heaven there are...

10 Ways to Practice Gratitude With Your family This Thanksgiving

10 Ways to Practice Gratitude With Your family This Thanksgiving

This month we are entering a season which, in the United States, has been devoted to gratitude and thanksgiving for 400 years! While the Thanksgiving holiday has had a long and varied history within the United States, the practice of devoting sacrificial offerings,...

Don’t Let Ungratefulness Turn You Into a Spoiled American

Don’t Let Ungratefulness Turn You Into a Spoiled American

My frequent trips to developing nations always help me adjust my attitude. Just when I start to feel spoiled and entitled, I meet people from places like Congo, India and Honduras—and I realize just how blessed I am. This happened to me again last week during a trip...

The Power of Being Thankful

The Power of Being Thankful

One of the best ways to show God we love Him is to be thankful. When we express our deep gratitude to Him, it actually invites His presence onto our lives. Being thankful also neutralizes the enemy and brings victory into our situations no matter what the outcome....

Get Off Your Pew!

Get Off Your Pew!

As God’s clock inches closer to the final hour before His return, many people find themselves filled with angst, anxiety and despair. People are not sleeping well, many have fallen into depression and are feeling hopeless. These are the very days that we have been...

The Great Commission Can Set Us Free from Responsibility

The Great Commission Can Set Us Free from Responsibility

Read Time: 4 Minutes 28 Seconds While all of the stories we read in the Torah are meaningful, sometimes the events we read about can seem to hold more relevance, especially for those of us who are followers of Yeshua (Jesus) as Messiah. One such event is the calling...

RECENT ARTICLES

The Church’s Role in Preserving Freedom of Speech in America

Read Time: 3 Minutes 17 Seconds The controversy surrounding Kyrie Irving and his post of a tweet that claims the Jews in Israel are not the real Jews—that Black Africans are the real Jews—raises...
Count Your Blessings, For God Indeed is Good

Count Your Blessings, For God Indeed is Good

Read Time: 4 Minutes 42 Seconds Thanksgiving Day is just a few days away for U.S. Americans. It is a favorite holiday—perhaps only exceeded by Christmas—to gather with family and friends to watch parades, play (American) “football” and eat delicious food—often from...

Is Serial Killer Jeffrey Dahmer in Heaven?

Is Serial Killer Jeffrey Dahmer in Heaven?

https://www.youtube.com/watch?v=iFbfS03JkKY&t=1s Read Time: 3 Minutes, 10 Seconds Is it possible that behind the pearly gates of heaven there are murderers, pedophiles and cannibals walking along the streets of gold? We are taught in the book of Romans, "That if...

Pin It on Pinterest